Jones names side for Canada Test
Four players will make their England debuts, after 12 received their first cap in Sunday's 43-29 win over USA.
Backs Dan Kelly (inside centre) and Adam Radwan (left wing), join Harry Wells (lock) and Alex Dombrandt at No. 8 for their first England appearances.
Lewis Ludlow will again captain the side at blind-side flanker, with Sam Underhill at open-side flanker.
Jamie Blamire (hooker) makes his first England start, with props Joe Heyes and Ellis Genge, who is vice-captain, and Charlie Ewels (lock) completing the tight five.
In attack, Marcus Smith stays at fly half and Harry Randall at scrum half. Henry Slade continues at outside centre, Freddie Steward is full back and Joe Cokanasiga is on the right wing.
Curtis Langdon, Beno Obano, Paul Hill, Callum Chick, Lewis Ludlam, Dan Robson, George Furbank and Joe Marchant make up the finishers.
Jones said: "Our focus this camp is being as strong a 36-player squad as we can be and there has been a lot of hard work and intense competition.
"There is a responsibility on the 23 players selected to perform to their personal best.
"We want to go out there and put smiles on the faces on all the supporters watching at Twickenham and at home on Channel 4."
England v Canada is live on Channel 4, with coverage starting from 2.30pm and kick-off at 3pm.
15. Freddie Steward (Leicester Tigers, 1 cap)
14. Joe Cokanasiga (Bath Rugby, 10 caps)
13. Henry Slade (Exeter Chiefs, 39 caps)
12. Dan Kelly (Leicester Tigers, uncapped)
11. Adam Radwan (Newcastle Falcons, uncapped)
10. Marcus Smith (Harlequins, 1 cap)
9. Harry Randall (Bristol Bears, 1 cap)
1. Ellis Genge (Leicester Tigers, 29 caps)
2. Jamie Blamire (Newcastle Falcons, 1 cap)
3. Joe Heyes (Leicester Tigers, 1 cap)
4. Harry Wells (Leicester Tigers, uncapped)
5. Charlie Ewels (Bath Rugby, 22 caps)
6. Lewis Ludlow (C) (Gloucester Rugby, 1 cap)
7. Sam Underhill (Bath Rugby, 23 caps)
16. Curtis Langdon (Sale Sharks, 1 cap)
17. Beno Obano (Bath Rugby, 2 caps)
18. Paul Hill (Northampton Saints, 5 caps)
19. Callum Chick (Newcastle Falcons, 1 cap)
20. Lewis Ludlam (Northampton Saints, 9 caps)
21. Dan Robson (Wasps, 13 caps)
22. George Furbank (Northampton Saints, 3 caps)
23. Joe Marchant (Harlequins, 5 caps)